Cyclobenzaprine: MedlinePlus Drug Information

Cyclobenzaprine is used to help relax certain muscles in your body. It helps relieve pain, stiffness, and discomfort caused by strains, sprains, or injuries to your muscles. However, this medicine does not take the place of rest, exercise or physical therapy, or other treatment that your doctor may recommend for your medical problem. Cyclobenzaprine acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of this medicine’s side effects.

Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Flexeril withdrawal symptoms can include headache, nausea, fatigue, and cravings for the drug. The efficacy of FLEXERIL 5 mg was demonstrated in two seven-day, double-blind, controlled clinical trials enrolling 1405 patients. One study compared FLEXERIL 5 mg and 10 mg t.i.d. to placebo; and a second study compared FLEXERIL 5 mg and 2.5 mg t.i.d. to placebo.

Struggling With Porn Addiction?

Tell your care team if your symptoms do not start to get better or if they get worse. Talk to your care team about the use of this medication in children. There are other drugs available to treat your condition. Talk with your doctor about other drug options that may work for you.

Prescribing Cyclobenzaprine for Long-Term Pain Management – PracticalPainManagement.com

Prescribing Cyclobenzaprine for Long-Term Pain Management.

Posted: Mon, 09 Apr 2018 07:00:00 GMT [source]

If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Cyclobenzaprine is structurally and pharmacologically related to tricyclic antidepressants. Among the most dreaded toxicities linked with cyclical antidepressants, overdoses affect fast-acting sodium channels in the cardiac conduction system. Cyclical antidepressants block the cardiac sodium channel and cause prolongation of cardiac depolarization, which manifests as QRS widening on electrocardiograms.

More common side effects

Skeletal muscle relaxants like cyclobenzaprine and methocarbamol can cause dizziness and drowsiness. Therefore, you should wait and see how these medications affect you before driving a motor vehicle or operating machinery. Drug comparisons between cyclobenzaprine and methocarbamol in terms of side effects do not reveal many differences.

In a pharmacokinetic study of sixteen subjects with hepatic impairment (15 mild, 1 moderate per Child-Pugh score), both AUC and Cmax were approximately double the values seen in the healthy control group. Based on the findings, FLEXERIL should be used with caution in subjects with mild hepatic impairment starting with the 5 mg dose and titrating slowly upward. Due to the lack of data in subjects with more severe hepatic insufficiency, the use of FLEXERIL in subjects with moderate to severe impairment is not recommended. Older adults may be more sensitive to the side effects of this drug, especially drowsiness, confusion, constipation, or trouble urinating. Drowsiness and confusion can increase the risk of falling.

  • Flexeril produces a variety of anticholinergic effects in high doses, altering the activity of brain neurotransmitters.
  • Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction.
  • Prior to splitting, each whole tablet was weighed on a special scale and the weight was recorded.
  • Taking this drug with an MAOI or within 14 days of stopping an MAOI could increase your risk of serious side effects.

Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Talk to your doctor if you are using marijuana (cannabis). The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. It may not be safe to breast-feed while using this medicine. Don’t take this medicine for longer than three weeks without talking to your doctor.

This page will go over its side effects, drug interactions, and treatment for misuse. Sometimes, muscle relaxants like cyclobenzaprine are used “off-label” to treat conditions they’re how long flexeril stay in system not approved for, such as fibromyalgia. Tell the doctor and pharmacist about all of your child’s drugs (prescription or OTC, natural products, vitamins) and health problems.

Cyclobenzaprine HCl relieves skeletal muscle spasm of local origin without interfering with muscle function. It is ineffective in muscle spasm due to central nervous system disease. Acute recovery phase of myocardial infarction, and patients with arrhythmias, heart block or conduction disturbances, or congestive heart failure. All patients suspected of an overdose with FLEXERIL should receive gastrointestinal decontamination.